Hemopoietic stem cell transplantation (HSCT) was developed in the early 1970s and was recognised as a potential treatment for a number of benign and malignant haematological diseases. Since then, the field has grown into a full specialty. Keeping pace with technological advances, this area has also seen evolution as regards to indications, availability of donor in family (an HLA identical sibling) or outside HLA matched unrelated donor (with the help of bone marrow donor registries) or haploidentical donor from parent or sibling.
In India, this treatment was started in 1983. The progress was slow initially, but has picked up in the last two decades. Currently, more than 110 centres are doing transplant. As per the Indian Society of Blood and Marrow Transplantation Registry, 23,843 patients underwent HSCT till 2021. Of these, 13,962 underwent allogenic HSCT (using stem cells from a donor), and 9,881 autologous HSCT (using patient's own stem cells). Multiple myeloma and lymphomas (Hodgkin's and Non Hodgkin's) are major indications for autologous HSCT, while acute myeloblastic leukemia (AML),ẞ-Thalassemia, severe aplastic anaemia and acute lymphoblastic leukemia are major indications for allogeneic HSCT.
هذه القصة مأخوذة من طبعة December 01, 2024 من THE WEEK India.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك ? تسجيل الدخول
هذه القصة مأخوذة من طبعة December 01, 2024 من THE WEEK India.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك? تسجيل الدخول
Forging the future
As the curtain falls on 2024, I take pride in the extraordinary milestones achieved under the leadership of Prime Minister Narendra Modi. This year stands as a testament to the Modi government's resolve to forge a resilient and forward-looking Bharat. From groundbreaking advancements in infrastructure to visionary global initiatives, these efforts resonate deeply with the vision of Viksit Bharat.
Our strange democracy
Abraham Lincoln is lauded as among the very best presidents the US ever had: the statesman par excellence successfully steered the nation through the devastating and perilous years of the American civil war. Not only did Lincoln manage to keep his country united, he also ensured the passage of the 13th amendment to the US constitution, which abolished slavery.
Five years of post-pandemic fashion
It has been five years since we discovered what Covid-19 was, and five years since it disrupted the world forever. The World Health Organization activated their emergency systems on January 1, 2020, and informed the world by January 4, 2020. By the end of that week, they had set guidelines for various countries to follow. Comparable to the Spanish flu of 1918, more than 7 million people have died of Covid according to official data. Unofficially, no one has an idea. WHO has just this week asked China to provide critical data to understand the virus's origins as a “moral and scientific imperative”.
Community spirit
Rhythm of Dammam opens a window to the world of African-origin Siddis of Uttara Kannada
'Breaking' down a scandal
Society Girl is not just a case study of a high-profile death in Pakistan but also a stark commentary on media trials
Progress card
Jasmine Shah's book tells you what the AAP has achieved in Delhi in the last 10 years
SENSE IN NONSENSE
In his latest book of poetry, Ruskin Bond is at his funniest
Get ready for Trump bump
The ‘butterfly effect’ is a beautiful, mysterious metaphor of the planet’s interconnectedness.
QUIET FLOWS THE FAITH
The melding of an ancient amorphous faith and the latest science; of an antique tradition and new practices; ways of life older than memory and new expressions is happening at Prayagraj in Uttar Pradesh.
Trash to treasure
How a weed-choked Dal Lake spurred Maninder Singh's journey to become a waste management visionary
