Tracking a new high
Designed to target -μ-opioid receptors in the brain, they were intended as next-generation painkillers with greater efficacy than morphine. However, their extreme potency and high risk of respiratory depression led to their rejection for medical use.
For nearly six decades, Nitazenes remained confined to academic research as “tool drugs” for studying opioid receptor pharmacology. That changed in 2019 when illicit labs began producing analogues (a drug that shares structural or pharmacological similarities with an existing drug) based on historical pharmacological research. These powerful compounds quickly infiltrated drug markets, particularly in Europe and North America, with little public awareness compared to heroin or MDMA. Nitazenes soon became a significant addition to the evolving landscape of “new psychoactive substances” (NPS).
هذه القصة مأخوذة من طبعة April 06, 2025 من THE WEEK India.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك ? تسجيل الدخول
هذه القصة مأخوذة من طبعة April 06, 2025 من THE WEEK India.
ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.
بالفعل مشترك? تسجيل الدخول
All eyes on Russia
A popular legend in Slavic folklore is the myth of Baba Yaga.
The man behind the myth
A new book brings alive the unknown side of LTTE leader Velupillai Prabhakaran
Menopause is not an end, but another period
Q/What is menopause?
The opportunity in the crisis
TARIFFS ARE IMPOSED by countries to protect domestic industry and, to a lesser extent, raise revenue.
Understanding of menopause within medical community is variable
The Indian Menopause Society (IMS) is a multidisciplinary national society committed to fostering the comprehensive well-being of the mature and elderly Indian women. Excerpts from an interview with IMS president Dr Anita J. Shah, a gynaecologist in Surat since 1988.
Count the sheep
Sleep impacts physical and mental health, yet it remains a low priority
India and Europe need to look at new alliances
THE WORLD IS CHANGING. It is highly unstable with geopolitical tensions that would last long term.
Justice on trial
Unless the Supreme Court takes full control of the process to remove corrupt judges of constitutional courts, the political class will step in
The welfare worry
The cost of populist schemes has Maharashtra reeling; Karnataka and Telangana, too, are struggling to foot the welfare bill
