New nanoparticle can diagnose, treat plaque in arteries: Study
The Straits Times|November 11, 2024
Developed by NUS researchers, it may hold key to preventing cardiovascular diseases
Zhaki Abdullah
New nanoparticle can diagnose, treat plaque in arteries: Study

New microscopic particles – less than a thousandth of a millimetre in size – could hold the key to preventing cardiovascular diseases such as coronary heart disease and ischaemic stroke.

Researchers from the NUS Yong Loo Lin School of Medicine (NUS Medicine) have developed a nanoparticle that can diagnose the build-up of plaque in the arteries, otherwise known as atherosclerosis, as well as target atherosclerotic plaques and deliver therapeutic agents.

A nanoparticle is a material with a diameter of between one and 100 nanometres, which is one-billionth of a metre.

These new nanoparticles break down in the acidic environment of atherosclerotic plaques and release gadolinium – a chemical that acts as a contrast agent, improving visualisation for magnetic resonance imaging, or MRI – allowing for real-time imaging of plaque severity.

Additionally, these miniscule particles are able to simultaneously deliver simvastatin, an anti-inflammatory drug that contributes to plaque stabilisation and treatment, thus reducing the risk of cardiovascular events.

The findings were published in nanoscience journal Small in August.

هذه القصة مأخوذة من طبعة November 11, 2024 من The Straits Times.

ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.

هذه القصة مأخوذة من طبعة November 11, 2024 من The Straits Times.

ابدأ النسخة التجريبية المجانية من Magzter GOLD لمدة 7 أيام للوصول إلى آلاف القصص المتميزة المنسقة وأكثر من 9,000 مجلة وصحيفة.

المزيد من القصص من THE STRAITS TIMES مشاهدة الكل
BACKFLIPPING THEIR WAY TO EQUALITY
The Straits Times

BACKFLIPPING THEIR WAY TO EQUALITY

The women were competing, finally, at Red Bull Rampage in Virgin, Utah, considered the biggest and gnarliest mountain bike competition in the world.

time-read
2 mins  |
November 14, 2024
The Straits Times

Biden meets Trump at White House for transition talks

President Joe Biden hosted President-elect Donald Trump at the White House on Nov 13 in a meeting designed to demonstrate a smooth transition between administrations, even though Trump's team has yet to sign documents to start the handover process.

time-read
2 mins  |
November 14, 2024
The Straits Times

Song Jae-rim made debut with K-drama The Moon Embracing The Sun

South Korean actor Song Jae-rim, who acted in blockbuster television dramas, including The Moon Embracing The Sun (2012), died on Nov 12 at the age of 39.

time-read
1 min  |
November 14, 2024
UK writer Samantha Harvey wins with space novel Orbital
The Straits Times

UK writer Samantha Harvey wins with space novel Orbital

British writer Samantha Harvey (right) won the prestigious Booker Prize on Nov 12 for her short novel following six astronauts as they contemplate Earth from the International Space Station.

time-read
1 min  |
November 14, 2024
Singer Penny Tai has vertigo, but still game to put on concert
The Straits Times

Singer Penny Tai has vertigo, but still game to put on concert

Malaysian singer Penny Tai has said a health issue prevents her from doing big movements.

time-read
1 min  |
November 14, 2024
S'porean actor Chin Han joins cast of Netflix series Avatar: The Last Airbender
The Straits Times

S'porean actor Chin Han joins cast of Netflix series Avatar: The Last Airbender

Netflix has expanded the cast of live-action series Avatar: The Last Airbender in its second season, with Singapore actor Chin Han one of the latest eight additions.

time-read
2 mins  |
November 14, 2024
Tenor Christoph Pregardien's Schubert recital simply spellbinding
The Straits Times

Tenor Christoph Pregardien's Schubert recital simply spellbinding

CONCERT CHRISTOPH PREGARDIEN SINGS SCHUBERT'S DIE SCHONE MULLERIN

time-read
2 mins  |
November 14, 2024
Puppet masters keep niche art form alive
The Straits Times

Puppet masters keep niche art form alive

The Finger Players, Paper Monkey Theatre and puppeteer Bright Ong are taking puppets to a wider audience

time-read
4 mins  |
November 14, 2024
All We Imagine As Light tells a humane tale, Red One delivers overstuffed turkey
The Straits Times

All We Imagine As Light tells a humane tale, Red One delivers overstuffed turkey

Two Malayali nurses in Mumbai negotiate their daily working-class grind. Dwayne Johnson and Chris Evans team up on a search-and-recovery operation when Santa Claus is abducted, mere days before Christmas Eve.

time-read
2 mins  |
November 14, 2024
Crime comedy takes a stab at wellness culture
The Straits Times

Crime comedy takes a stab at wellness culture

MURDER MINDFULLY Netflix ★★★★☆

time-read
2 mins  |
November 14, 2024