Hunting Delta

The U.S. system for tracking Covid variants is scattered and slow. Time to fix it

- Cynthia Koons

There’s no good place to stand inside the Pandemic Response Lab’s sequencing facility in Queens, N.Y. Take a wrong step, and you’re blocking a gowned-up lab tech as she ferries a plate with the RNA from 384 Covid-19 test samples to a machine that runs a polymerase chain reaction (PCR) test, identifies positives, and extracts them with a robotic arm. A data scientist hurries by, bringing more RNA samples to a device that will convert them into DNA. In the corner are genomic sequencing machines that piece together chopped-up bits of that DNA to identify what form of SARS-CoV-2 a patient has. Name a mutation you’ve heard of, and this lab has seen it, as it takes part in the national and global efforts to sequence virus genomes, spot new and dangerous variations, and stem their spread.