The chilling warning from United Nations secretary-general Antonio Guterres came as Russia accused the US for the first time of direct involvement in the war in Ukraine.
Mr Guterres said Vladimir Putin's invasion of Ukraine and tensions on the Korean peninsula and in the Middle East had caused a state of peril not seen since the Cold War.
Consequences
He said rising global conflict meant "humanity is just one misunderstanding, one miscalculation away from nuclear annihilation".
Opening a conference in New York for nuclear non-proliferation treaty nations, Mr. Guterres said: "We have been extraordinarily lucky so far."
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