Scientists Unravel Why Some People Are More Susceptible To Covid-19
The Hindu Business Line|April 13, 2020
Findings may help make a drug to fight the deadly infection
T V Jayan
Scientists Unravel Why Some People Are More Susceptible To Covid-19

A team of researchers from India and the US, led by a scientist at the Chennaiheadquartered private genome research foundation, has found why some individuals are more susceptible to COVID-19 infection than others.

Researchers from MedGenome Inc and SciGenom Research Foundation (SGRF) jointly anlaysed the DNA sequence and variation data from over 300,000 individuals belonging to 400 different populations to predict susceptibility to the COVID-19 disease caused by the SARS CoV-2 virus. Nearly 1 per cent of the samples are from people of Indian origin.

The team led by Sekhar Seshagiri, President of Chennai-based SGRF India, identified variations in the angiotensin-converting enzyme 2 (ACE-2) protein gene that are predicted to make individuals more susceptible to the virus. Their findings are published online on the Biorxiv.org portal. However, the study is yet to be peer-reviewed.

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