With extensive rail engineering works planned, followed by train strikes, many travellers will be left with no option but to drive.
And plane and ferry passengers have been warned to expect delays due to the sheer number of people heading off on breaks.
There will be no respite the following weekend, with delays predicted on roads and at ports and airports.
Simon Williams, from the RAC, said: "It's a double whammy of back-to-back weekends with disrupted travel, with a very busy Easter holiday on the roads plus rail works, and then rail strikes the next weekend.
"Strikes mean people who booked trains are in the unenviable position of cancelling trips to families and friends, or being forced to take the car instead.
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