Novel molecules fight viruses by bursting their bubble-like membranes
Scientific India|July-August 2023
Antiviral therapies are notoriously difficult to develop, as viruses can quickly mutate to become resistant to drugs. But what if a new generation of antivirals ignores the fast-mutating proteins on the surface of viruses and instead disrupts their protective layers?
Novel molecules fight viruses by bursting their bubble-like membranes

Researcher have found an Achilles heel of many viruses: their bubble-like membranes. Exploiting this vulnerability and disrupting the membrane is a promising mechanism of action for developing new antivirals.

In a new study published in the journal ACS Infectious Diseases, the researchers show how a group of novel molecules inspired by our own immune system inactivates several viruses, including Zika and chikungunya. Their approach may not only lead to drugs that can be used against many viruses, but could also help overcome antiviral resistance.

The urgent need for new antivirals

Viruses have different proteins on their surfaces that are often the targets of therapeutics like monoclonal antibodies and vaccines. But targeting these proteins has limitations, as viruses can quickly evolve, changing the properties of the proteins and making treatments less effective. These limitations were on display when new SARS-CoV-2 variants emerged that evaded both the drugs and the vaccines developed against the original virus.

Diese Geschichte stammt aus der July-August 2023-Ausgabe von Scientific India.

Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.

Diese Geschichte stammt aus der July-August 2023-Ausgabe von Scientific India.

Starten Sie Ihre 7-tägige kostenlose Testversion von Magzter GOLD, um auf Tausende kuratierte Premium-Storys sowie über 8.000 Zeitschriften und Zeitungen zuzugreifen.

WEITERE ARTIKEL AUS SCIENTIFIC INDIAAlle anzeigen
An insight into Chandipura virus in India
Scientific India

An insight into Chandipura virus in India

Recently lot of news regarding disease due to Chandipura virus has emerged in various newspapers/magazines. After reading the reports published it seems that thing is still brewing in the natures nest and it could affect mankind.

time-read
3 Minuten  |
September - October 2024
Why elephants never forget?
Scientific India

Why elephants never forget?

An elephant has a very large brain for its size and the 'temporal lobe' region responsible for memory is more developed with a greater number of folds - this results in powerful abilities to 'download' important survival data such as where to find food and water, and who is friend or foe.

time-read
1 min  |
September - October 2024
Use of Algae for Wastewater Treatment Containing Heavy Metals
Scientific India

Use of Algae for Wastewater Treatment Containing Heavy Metals

Wastewater treatment is a critical environmental issue particularly when it comes to the removal of heavy metals.

time-read
3 Minuten  |
September - October 2024
Nano priming Seeds: A Small Innovation Sparkling Big Advances in Germination
Scientific India

Nano priming Seeds: A Small Innovation Sparkling Big Advances in Germination

Nanopriming is an emerging agricultural technique where the seeds are treated with nanoparticles to improve their germination, growth, and overall performance.

time-read
4 Minuten  |
September - October 2024
Nobel Laureates in Physics 2024: Revolutionizing AlThe Physics Foundations Behind Machine Learning
Scientific India

Nobel Laureates in Physics 2024: Revolutionizing AlThe Physics Foundations Behind Machine Learning

This year's two Nobel Laureates in Physics have used tools from physics to develop methods that are the foundation of today's powerful machine learning.

time-read
2 Minuten  |
September - October 2024
Revolutionizing Biology: The 2024 Nobel Prize in Chemistry Celebrates Breakthroughs in Protein Design and Structure Prediction
Scientific India

Revolutionizing Biology: The 2024 Nobel Prize in Chemistry Celebrates Breakthroughs in Protein Design and Structure Prediction

The Nobel Prize in Chemistry 2024 is about proteins, life's ingenious chemical tools.

time-read
2 Minuten  |
September - October 2024
New findings on animal viruses with potential to infect humans
Scientific India

New findings on animal viruses with potential to infect humans

Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses.

time-read
2 Minuten  |
September - October 2024
Father-Daughter Team Decodes Mars' Alien Signal
Scientific India

Father-Daughter Team Decodes Mars' Alien Signal

There is no definitive answer to whether aliens exist, but there is a lot of work being done to find out:

time-read
2 Minuten  |
September - October 2024
Krishi Vigyan Kendras: Working for Farmer's Welfare
Scientific India

Krishi Vigyan Kendras: Working for Farmer's Welfare

Krishi Vigyan Kendras (Farm Science Centres) are the District level institution serving as an agriculture knowledge resource & capacity development centre which plays indispensable role in front line extension regarding agriculture system in scientific way.

time-read
4 Minuten  |
July-August 2024
Sixth generation Computer: The future computing technology
Scientific India

Sixth generation Computer: The future computing technology

We are in a transition towards a digital world, where everything will be dealt with in digital format.

time-read
4 Minuten  |
July-August 2024