Nowadays, we are seeing an increasing incidence of Non-Alcoholic Fatty Liver Disease (NAFLD), which is when there is excessive buildup of fat in the liver not related to alcohol excess. The incidence is about 40–50 percent in the population. This condition is related to hyperlipidaemia, diabetes and obesity, all part of the metabolic syndrome. Some believe NAFLD is the manifestation of metabolic syndrome in the liver. NAFLD is a spectrum that ranges from steatosis (fatty deposits in liver) to non-alcoholic steatohepatitis (NASH, where the excess fatty deposits cause hepatitis or inflammation of the liver), to NASH cirrhosis (where the repeated inflammation causes the liver to undergo fibrosis and harden). This is important, as cirrhosis can then lead to a fortyfold increased risk of liver cancer. It is important to pick up NAFLD early while in the steatosis stage and institute treatments and lifestyle changes before it progresses to NASH and NASH cirrhosis.
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