Assisted Reproductive Technology (ART) has made immense strides since the first live birth following In-vitro Fertilisation (IVF) in 1978. This multi-faceted improvement led to the optimisation of ovarian stimulation and a better assessment of embryo quality, giving rise to steady increase in live birth delivery rates.
The cumulative live birth rate after one oocyte retrieval cycle is considered the most accurate benchmark for ART success.
Empirical evidence shows that embryo evaluation based on morphology, morphokinetics, preimplantation genetic testing (PGT-A) or embryo metabolism, and microfluidics, all have the potential to rank embryos according to implantation potential.
We do not have high quality data showing the difference in ranking potential between these different methods to evaluate embryo quality. However, much of ongoing studies are based on these. The aim is to improve live birth rate or cumulative birth rate for most recent developments in ART.
IVF lab A perfect homeostasis is provided by in vivo micro environment during the course of blastocyst development. The same is mimicked in IVF lab.
Various commercial media companies recommend differing pH ranges, most within the range of 7.2–7.4. Most don’t reveal the secret composition of media and fall short of robust research to indicate best media composition and incubation parameters.
Historically, CO2 set-points in incubators are adjusted to attempt to create the ideal media pH environment for any development stage of embryos. CO2 adjustments are usually done by calibrating the pH of equilibrated media once a month or once a week. There are many gadgets for pH measurement for IVF culture systems. A bench top pH meter can be used for the routine pH measurement with proper calibration buffers.
However, it is essential to keep the certificate of analysis of the media being used. A new technology, SAFE Sens Trak Station, enables real time non-invasive pH monitoring within an incubator environment.
Use of this technology can reveal about incubator conditions which are not ideal for maintaining ideal pH levels. Use of RFID tags precludes the errors in the lab.
Esta historia es de la edición December 2018 de eHEALTH.
Comience su prueba gratuita de Magzter GOLD de 7 días para acceder a miles de historias premium seleccionadas y a más de 9,000 revistas y periódicos.
Ya eres suscriptor ? Conectar
Esta historia es de la edición December 2018 de eHEALTH.
Comience su prueba gratuita de Magzter GOLD de 7 días para acceder a miles de historias premium seleccionadas y a más de 9,000 revistas y periódicos.
Ya eres suscriptor? Conectar
Preventing The Spread Of Coronavirus From Contaminated Medical Devices
Highly contagious novel Coronavirus first reported in China’s Wuhan city has sent shockwaves worldwide with scientists working on vaccines to contain the virus.
Patients' Privacy & Data Threat In Digital Era
With healthcare service providers leveraging various digital tools, connected devices, and automated processes to bolster patient care, data privacy and security have emerged as major threat nowadays. As large amount of data is exchanged at various levels especially in form of EHR, and other clinical information, personal data of patients remain at stake which needs to be preserved from prying eyes of cyber attackers. Mukul Kumar Mishra of Elets news Network (ENN) explores various facets of data security, associated challenges and possible way out.
TeleHealth—Powerful Tool to Achieve Universal Healthcare & Holistic Wellness
Telehealth has emerged as a viable tool for healthcare providers to improve accessibility, provide remote care, and helping governments in achieving Universal Healthcare, writes Vikram Thaploo, CEO – TeleHealth, Apollo Hospitals Enterprises Limited, for Elets News Network (ENN).
‘Personalized Attention is at Core of Our Patient Care Philosophy'
Continental Hospitals is a NABH-JCI accredited multi-speciality quaternary care hospital with a capacity of 750 beds. With the state-of-the-art facilities, advanced medical equipment combined with the latest technology, the hospital ensures utmost comfort and safety to patients, says Dr Rahul Medakkar, CEO, Continental Hospitals, in conversation with Mukul Kumar Mishra of Elets news Network (ENN).
‘Enabling Hospitals to Unleash Full Potential of Caregiving'
DayToDay is a care management company that provides platform to clinicians to extend their reach beyond hospital walls and deliver world-class care to patients in the comfort of their homes, says Prem Sharma, CEO & Founder, DayToDay, in conversation with Gopi Krishna Arora and Mukul Kumar Mishra of Elets News Network (ENN).
Future & Importance of Clinical Analytics
Clinical analytics is poised to become an essential tool that makes use of real-time medical data to generate insights, take decisions, predict outcomes, and decrease costs by enabling early interventions for potential clinical complications, writes Abdullah Saleem, Group, CIO, Omni Hospitals for Elets News Network (ENN).
Role of Emerging Technology in Building Smart Hospitals
In the wake of huge patients’ expectations pertaining to quick service, less waiting time and hassle free comprehensive experience, smart hospitals hold a huge significance today. With cutting-edge technologies like AI and ML, these hospitals are automating and optimizing various processes to ensure best care to masses, writes Dr Mervin Leo, COO, Aware Gleneagles Global Hospitals, L B Nagar, Hyderabad for Elets News Network (ENN).
AIIMS — Adopting Several Reforms to Bring Quantum Leap in Patient Care
All India Institute of Medical Science (AIIMS), Delhi, one of the premier medical institutes across country, has come of age delivering accessible and quality services to masses. With new OPD block, several reforms, and optimizing various processes, and the Institute is set to transform delivery of healthcare services, says Subhsish Panda, Deputy Director, AIIMS, in conversation with Nisha Samant & Mukul Kumar Mishra of Elets news Network (ENN).
‘1.5 lakh Sub Centres to be Converted into Wellness Centres by 2022'
Health is the biggest wealth one could ever have. Human health is priceless.
‘Accountablity, Management & Strategy Key to Bolster Patient Care'
Accountability and work management coupled with robust strategy can do away major issues affecting the delivery of healthcare in Uttar Pradesh, said Atul Garg, Minister of State, Medical, Health & Family Welfare, Mother and Child Welfare,
