An international team of researchers has found a new and unique approach to improving the anti-cancer effect of a new medicine class called 'Smac mimetics'.
Firstly, the researchers found that a protein called MK2 which aids in keeping cancer cells alive by making them resistant to the anti-cancer effects of Smac mimetics. Their findings have provided the ground to combine inhibitors of MK2 with Smac mimetics which according to researchers is a potentially powerful new combination therapy for cancers with few treatment options, such as acute myeloid leukemia (AML).
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