ALEX MITCHELL has been ruled out of England's Six Nations clash with Scotland on Saturday, in another setback for coach Steve Borthwick.
Scrum-half Mitchell, who started wins over Italy and Wales, has a knee injury and will be assessed this week.
Bristol's Harry Randall has been promoted from the A squad as cover for Danny Care and Ben Spencer at scrum-half.
Borthwick has been boosted by the return to full fitness of Bath centre Ollie Lawrence, who has finally shrugged off a hip injury and joins fit-again Manu Tuilagi in the squad.
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