Saracens hooker George will lead England for the first time as official skipper here in Rome.
Flanker Ethan Roots (below) and centre Fraser Dingwall will make their Test debuts from the off, while Chandler Cunningham-South, Fin Smith and Immanuel Feyi-Waboso should also win their first caps from the bench.
George will stay calm and collected until roughly 10 minutes before the warm-up, opting to spend some time sat in the dugouts watching supporters file into the ground.
The 33-year-old knows that he will have to keep the emotion in check amid a significant personal achievement on the occasion of his 86th cap.
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