Nikita Thorne, 14, was last seen on Thursday at their home on Leominster Drive in Wythenshawe on Thursday at 4.40pm.
Her mother Catherine Robinson says Nikita was headed to the local shops at nearby Peel Hall Road but "never returned".
Nikita is described as white, 5ft 5in, medium build with long brown hair and brown eyes.
Her mother says Nikita left the house wearing make-up, which she may have taken off.
Esta historia es de la edición February 26, 2023 de MEN on Sunday.
Comience su prueba gratuita de Magzter GOLD de 7 días para acceder a miles de historias premium seleccionadas y a más de 9,000 revistas y periódicos.
Ya eres suscriptor ? Conectar
Esta historia es de la edición February 26, 2023 de MEN on Sunday.
Comience su prueba gratuita de Magzter GOLD de 7 días para acceder a miles de historias premium seleccionadas y a más de 9,000 revistas y periódicos.
Ya eres suscriptor? Conectar
Defensive pair still out with Rico return likely
MANCHESTER City travel to Ipswich Town in the Premier League on Sunday seeking to bounce back from their late collapse at Brentford.
This is my gift...
CYNDI LAUPER REFLECTS ON HER CAREER AHEAD OF THE UK LEG OF HER FAREWELL TOUR.
FACE THE FUTURE
We round up five fabulous finds from this year's Consumer Electronics Show
JILL'S COFFEE BAR ON THE WRIGHT TRACK
ENGLAND football legends united in Greater Manchester as Ian Wright paid a surprise visit to the popular cafe owned by Lionesses star Jill Scott.
Maria was the therapy I didn't realise I needed
FOLLOWING Maria Callas's death, aged just 53, many reflected on the life and career of the incredibly talented opera singer as one of great tragedy.
Law gave fans the time of their lives
IT IS rare for a footballer to be a great, a legend and a king. Denis Law was all three.
Two teens in custody after 16-year-old stabbed
TWO teenagers have been arrested after a 16-year-old boy was stabbed in Clayton.
PSG star signing won't be available for City showdown
MANCHESTER City and PSG meet in the French capital next Wednesday in a fixture crucial for both clubs' seasons.
Curious case of a 48-hour art heist
IT'S a Sunday morning, just before noon, and staff at Manchester's Whitworth Art Gallery are about to open up for the day when a barely believable discovery is made.
February games are chosen for TV coverage
MANCHESTER City's FA Cup trip to Leyton Orient and Premier League game against Tottenham Hotspur in February have been chosen for TV coverage.