Manchester United signed off Ruud van Nistelrooy's temporary stint in charge with a 3-0 win over Leicester and Nottingham Forest dropped out of the top four after a 3-1 home defeat to Newcastle.
Arsenal are now winless in four Premier League games as their bid for a first title since 2004 is at risk of unravelling.
The Gunners welcomed captain Martin Odegaard back to the starting line-up for the first time in two months and were much improved at Stamford Bridge, but still could not come away with a vital three points.
Odegaard teed up Gabriel Martinelli to open the scoring with a near-post shot on the hour mark.
Chelsea responded through Pedro Neto's long-range effort for his first league goal since a £51 million move from Wolves.
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A front-row seat to the rich tapestry of nature
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The song remains the same
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Clean sweep beckons
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Recognising burgeoning talent
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Deputy Howley backs Gatland to get Wales out of trouble
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Flyhalf is very 'Sexton-esque'
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Scottish success riding on Aussie Test
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French defeat is hard to swallow
ALL BLACKS: SHOWING HEALTHY RESPECT FOR AZZURRI
