Eriksen's 35th-minute blast put United ahead, but the Danish midfielder gifted Twente their second-half equaliser at Old Trafford.
Sam Lammers dispossessed Eriksen, who had made a risky turn under pressure, and fired past Andre Onana in the 68th minute.
United manager Ten Hag refused to single out Eriksen, instead insisting the whole team had to take responsibility for their failure to hold onto the lead.
"We kept them alive, 1-0 up, controlling the game you have to be consistent and keep going. In the second half we dropped the level, gave the goal away," Ten Hag said.
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