Dr. FeelGood and the Club Drug Cure

Is ketamine the best hope for curing major depression?

- Caroline Winter, photographs by Kevin Shea Adams

On the seventh floor of a building overlooking the Federal Reserve Bank in lower Manhattan, two medical clinics share an office. One is run by a podiatrist who’s outfitted the waiting room with educational materials on foot problems such as hammer toes and bunions. The other clinic doesn’t have pamphlets on display and offers a much less conventional service: For the advertised price of $525, severely depressed and suicidal patients can get a 45-minute intravenous infusion of ketamine better known as the illicit party drug Special K. Glen Brooks, a 67-year-old anesthesiologist, opened NY Ketamine Infusions in 2012. “At least eight or nine of my patients have ended up making appointments with the podiatrist,” he says. “But I haven’t gotten any patients through him I don’t know why.” Not that Brooks is lacking for business. He typically treats 65 patients a week. Most come in for an initial six infusions within a span of two weeks, then return every six to eight weeks for maintenance sessions. To keep up with demand, he often borrows rooms from the podiatrist on weekends so he can treat eight patients at once. His only help is a secretary at the front desk.

Patients don’t need a prescription, but not just anyone can get an appointment. “You have to have the right story,” Brooks says. “For ketamine to work, there needs to be some preexisting brain damage caused by post-traumatic stress. I’m looking for some indication of childhood trauma. If not overt pain, then fear, anxiety, loneliness, low self-esteem—or bullying, real or perceived.” Patients receive a low dose of the drug: about one-tenth of what recreational abusers of ketamine take or about one-fifth of what might be used as a general anesthetic.