Why Mutants Are The X Factor In Vax Drive
The Times of India Delhi|April 10, 2021
In India’s first Covid wave last year, virus mutations did not play a big role, but the second wave in India and abroad is being shaped by new and emerging “variants of concern” (VoC). In its new forms, the virus can spread faster, be more lethal or render vaccines less effective. A look at the variants reported in India and their impact on vaccination
Why Mutants Are The X Factor In Vax Drive

India’s ‘double-mutant’

Coronaviruses mutate constantly, and Indian scientists have reported an uncommon ‘double mutant’ that combines mutations from two separate virus variants.

Although it has been found in samples from Maharashtra, Punjab and Delhi — states that are seeing a surge in cases — the double mutant is not widespread enough to account for the massive increase in Covid cases, according to the ministry of health.

The first of its mutations is known as E484Q, and is similar to the E484K mutation found in VoCs from the UK, Brazil and South Africa. This mutation affects changes in the coronavirus’s spike protein, which helps it latch onto and infect human cells.

The second mutation, L452R, has also been found in variants in Denmark and California. It enhances the virus’s ability to bind to human cells, making it more infectious.

WHAT IT MEANS FOR VACCINES: Scientists are evaluating the double mutant’s impact on vaccine efficacy as both its mutations have been found – in specific cases – to make them less effective. At least with the South African variant, vaccines were found to considerably lower the chance of severe illness or death.

UK variant B.1.1.7

This story is from the {{IssueName}} edition of {{MagazineName}}.

Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 9,000+ magazines and newspapers.

This story is from the {{IssueName}} edition of {{MagazineName}}.

Start your 7-day Magzter GOLD free trial to access thousands of curated premium stories, and 9,000+ magazines and newspapers.

MORE STORIES FROM THE TIMES OF INDIA DELHIView all
Song and dance there, but where is Brazil's soul?
The Times of India

Song and dance there, but where is Brazil's soul?

From swooning over the twirling foot of Richarlison the other day, to fretting over the ankle of Neymar, it is back to business for Brazil. Gone is the exultation to dance and express themselves.

time-read
3 mins  |
November 28, 2022
Marriott to reach 200-hotel mark in India by 2025 from current 134
The Times of India

Marriott to reach 200-hotel mark in India by 2025 from current 134

American hospitality major Marriott International — the group with the largest number of branded hotel rooms in India at about 26,000 — has drawn up very ambitious growth plans for the country.

time-read
1 min  |
November 28, 2022
India's visually-impaired players dribble, debate on and off field
The Times of India

India's visually-impaired players dribble, debate on and off field

Take 20-year-old Shivam Negi for instance. A member of the national blind football team, Negi along with three other NIEVPD students is ardently following the matches by listening to live commentary.

time-read
1 min  |
November 28, 2022
SIPS eating into luxe car sales: Merc
The Times of India

SIPS eating into luxe car sales: Merc

‘MF Investments Reducing Disposable Incomes Of Indians’

time-read
1 min  |
November 28, 2022
Fury's Ground Xiro
The Times of India

Fury's Ground Xiro

Xi's zero-Covid policy has angered ordinary Chinese as never before. A dangerous moment for the state

time-read
3 mins  |
November 28, 2022
Trump faulted for dinner with white nationalist, rapper Ye
The Times of India

Trump faulted for dinner with white nationalist, rapper Ye

The sportswear manufacturer has also launched a probe into his conduct.

time-read
1 min  |
November 28, 2022
Blank sheets of paper become symbol of defiance
The Times of India

Blank sheets of paper become symbol of defiance

Chinese protesters have turned to blank sheets of paper to express their anger over Covid-19 restrictions.

time-read
1 min  |
November 28, 2022
Can't deny mediclaim to a vegetarian, insurer told
The Times of India

Can't deny mediclaim to a vegetarian, insurer told

Dietary Habit Not Patient’s Fault: Consumer Body

time-read
1 min  |
November 28, 2022
Thakur: Will host 'grand Olympics' in Gujarat in future
The Times of India

Thakur: Will host 'grand Olympics' in Gujarat in future

Union sports minister Anurag Thakur on Sunday said Gujarat will host a “grand Olympics” sporting event in the future.

time-read
1 min  |
November 28, 2022
Will restore old pension scheme in Guj: Kejriwal
The Times of India

Will restore old pension scheme in Guj: Kejriwal

He also urged government employees in the state to back AAP while promising implementation of the old pension scheme for them by January 31, 2022.

time-read
1 min  |
November 28, 2022