Trials Target Better Management Of Treatment-Resistant Depression
Singapore Business Review|Issue 108
Managing treatment-resistant depression (TRD) can take months to years, but Singapore is accelerating the process by embarking on trials of personalised transcranial magnetic stimulation (TMS) specifically tailored for Asian brains.
Trials Target Better Management Of Treatment-Resistant Depression

The Institute of Mental Health (IMH), which together with the Yong Loo Lin School of Medicine at the National University of Singapore (NUS Medicine) is spearheading the trials, defines TMS as a “non-invasive therapeutic modality that utilises magnetic fields to modulate neural activity in specific brain regions.”

The trials, namely Asia Pacific Individual Connectomics – Transcranial Magnetic Stimulation (APIC-TMS) and Singapore’s Precision Approach for Relief from Depression (SPARK-D), are modelled after the Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) protocol.

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