GRAIL’s MCED test analyzes DNA shed by both normal and cancerous cells into a person’s bloodstream, looking for telltale epigenetic changes that affect the way genes operate. Specific changes are associated with the presence of cancer cells.
Published research indicates that the test can detect a shared signal across more than 50 types of cancer. They include pancreatic, liver, and kidney cancers, which are difficult to diagnose early. The Galleri test not only detects a cancer signal but also provides two predictions of the cancer signal’s origin to inform further diagnostic evaluation.
MCED screening is a potentially significant advance because there are currently only five recommended cancer screening tests: for breast, colorectal, lung, cervical, and prostate cancers. Around 70 percent of new cancer diagnoses and deaths are due to cancers for which there are no recommended screening tests.
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