Paul Dawson gave the hosts the lead 14 minutes in, before Dylan Mottley-Henry equalized for the Mariners.
The tide looked to be turning against the Brig when Nathan Pond was sent off with 20 minutes left, but Sinclair-Smith’s effort gave Jamie Milligan’s side all three points.
Speaking after the game, Milligan said: “I thought overall we deserved to win the game today. In the first half, we played some really good football and showed what we are all about.
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