Ms Pelosi stressed that the US Congress would not back a trade deal with the UK if the Government persists with "deeply concerning" plans to "unilaterally discard" the protocol.
She issued the warning after Foreign Secretary Liz Truss announced plans to legislate to override parts of the Brexit withdrawal treaty the UK struck with the EU, to be able to unilaterally change the protocol.
Ms Pelosi said: "Negotiated agreements like the protocol preserve the important progress and stability forged by the Good Friday Accords, which continue to enjoy strong bipartisan and bicameral support in the United States Congress.
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