Vaughan joined former India coach Ravi Shastri in urging a shake-up which would include relegation and promotion to help ensure the survival of the red-ball game.
Both men were on commentary duties during the thrilling five-Test series between Australia and India which the hosts won 3-1 in front of huge crowds.
"It has been a series that has only served to strengthen my views on where the game is headed and what administrators should be looking at," Vaughan said in a column for The Telegraph in London and The Sydney Morning Herald.
"I believe it is a four-day product with a set number of overs each day enforced, three matches minimum per series and two divisions of six, including promotion and relegation."
Shastri said the Australia-India series proved Test cricket continued to hold its own in the face of ever-increasing T20 franchise cricket.
But, like Vaughan, it only reinforced his view that to survive, the biggest teams needed to be playing each other more often.
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