The two collide in Riyadh on Saturday night, with the winner becoming the first man to rule the division since Lennox Lewis in 2000 and the first to hold the WBC, WBA, IBF and WBO titles simultaneously.
The 'Gypsy King' has a sixinch height advantage and an extra seven inches in reach and Frampton, Northern Ireland's former two-weight world champion, believes he must impose himself on the Ukrainian.
"I think we'll see a good Tyson Fury and an aggressive one. He will be on the front foot like in his second and third fights against Deontay Wilder," Frampton said.
"You could question if Fury is able to get up on his toes like he used to. The size of the man, it's got to be sore on ankles and knees if he does move a lot.
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