The all-rounders have signed overseas contracts with the Red Rose and will be available to play in the LV= Insurance County Championship and Vitality T20 Blast throughout the season.
De Grandhomme, 36, will be available to play the first four matches of the County Championship campaign before he is joined by compatriot Mitchell, who arrives before their clash with Somerset on May 11.
Both will be available for the Lightning for the entirety of the Blast and Mitchell’s arrival will come in preparation for New Zealand’s white-ball tour of England in August and September.
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