West Midlands Police said they held a 22-year-old in Birmingham city centre just after midnight yesterday while a second man aged 21 was arrested in London several hours later.
They are to be questioned on suspicion of murdering Mr Fisher, who was out with friends at a nightclub called Crane in Digbeth when he was stabbed.
Officers said they were called to the club at around 11.45pm on Boxing Day and despite efforts to save him, Mr Fisher died 30 minutes later.
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