But it's a fourth straight loss in this championship for Italy, who need to win in Scotland next weekend in the final round to stand a chance of avoiding finishing bottom of the standings.
The likelihood is, however, the Italians will be last for an eighth straight year in the Six Nations and the 18th time in 24 editions since joining the tournament in 2000.
Their 25th successive Six Nations home loss had its origins in another, now trademark sloppy first half, with Wales – piloted by the excellent Webb at scrum-half in his first test start in three years – soaring ahead 10-0 after 10 minutes and holding a 22-3 lead by halftime.
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