Glucagon-like peptide-1 (GLP-1) receptor agonists are a family of medications that help people shed the pounds, manage blood sugar in patients with type 2 diabetes and prevent heart attacks and strokes in people with heart disease.
But while the benefits of the drugs for treating obesity, type 2 diabetes and cardiovascular disease are well known, their potential impact on kidney health has been less certain.
Now the largest and most comprehensive analysis of GLP-1 receptor agonists on kidney outcomes suggests they could have significant benefits. The findings were published in the Lancet Diabetes & Endocrinology journal.
Researchers conducted a meta-analysis of 11 large-scale clinical trials of weight-loss drugs involving more than 85,000 people. The group included people with type 2 diabetes, and people with cardiovascular disease who were overweight or obese but did not have type 2 diabetes.
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