The past three editions of this fixture had all finished in a 1-1 draw and this match yesterday had seemed destined to follow suit, after Ethan Pinnock's own goal had cancelled out Bryan Mbeumo's opener in the first half and Eberechi Eze's free-kick at 0-0 was bizarrely ruled out.
However, on an afternoon when Thomas Frank had taken the bold decision of leaving Ivan Toney out of his match-day squad as the England striker attempts to engineer a move away, it was Wissa - the club's top scorer last season who proved to be the match winner when he forced the ball home from close range 14 minutes from time.
Not since a League Cup tie in 1977 had Brentford beaten their London rivals, while you had to go back even further to 7 September 1963 - for their last league win against Palace in the old Division Three.
Yet after a summer during which he has already lost Michael Olise to Bayern Munich as doubts grow over the future of Marc Guéhi, this under-par performance was perhaps a sign that things will not be so easy for Oliver Glasner after his spectacular start to life in south London last season.
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