Centre-half Elliott Moore headed home a corner in the 53rd minute to give the U’s victory in the first leg at the Kassam Stadium.
In front of a noisy sell-out 11,000 crowd, Oxford started on the front foot, Josh Murphy forcing a corner in only the second minute, and Ruben Rodrigues seeing his 15-yard shot saved moments later.
The U’s had finished their league campaign with a lot of momentum, winning five and drawing two of their past eight games, which included a 5-0 thrashing of Posh three weeks ago.
After taking the sting out of Oxford’s early dominance of the ball, Posh created an opening in the 18th minute for Ephron MasonClark to fire in a low angled shot from the left which Jamie Cumming got down comfortably to save.
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