Rising levels of COPD, including asthma are driving a lot of innovations in inhalers with an aim to improve the overall effective management of these diseases
Although medication and treatment for COPD and asthma are available in oral, injectable dosage forms as well, inhaled therapy is preferred globally, because of the high drug concentration which can be achieved locally within the lungs, with reduced risk of systemic side effects. Global clinical guidelines issued by the Global Initiative for Asthma (GINA) and the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommend that persistent, moderate-to-severe asthma and COPD at high risk of exacerbations be treated with a combination therapy of inhaled corticosteroid (ICS) and long-acting beta-agonist (LABA), administered via an inhaler. The guidelines also recognise that this therapy is best administered in a fixed-dose combination (FDC) from a single inhaler, rather than from two separate inhalers. This is demonstrated by reduced adherence and increased discontinuation rates in patients using multiple inhalers versus those using FDC devices. Thus, inhalers remain a major part of asthma treatment.
Trends in inhalers
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