Human trials will soon begin for a cancer vaccine developed by Stanford researchers
Cancer vaccines are back in the headlines with research teams from Stanford University School of Medicine publishing breakthrough results of immunotherapy studies. Cancer research seems to be experiencing a tidal wave of immunotherapy treatment options; the excitement around the US Food and Drug Administration approval of the first CAR T-cell therapy and then a second one within months, is still afresh. The Stanford teams are taking this to a new level by pressing all the right buttons for a cancer vaccine.
This February, an interesting study led by researchers at the university has shown experimental vaccines as possible treatments for cancers in mice, and the university is starting human trials soon.
Stimulating immune system against solid tumours
The study injected minute amounts of two immune-stimulating agents directly into solid tumours in mice and found that this could eliminate all traces of cancer in the animals, including distant, untreated metastases.
“When we use these two agents together, we see the elimination of tumours all over the body,” said Ronald Levy, MD, professor of oncology and senior author of the study, in the Stanford press release.
The cancer environment displays a strange kind of relationship with the immune system. Immune cells like T-cells recognise the abnormal proteins present on the surface of cancer cells and infiltrate the cells to attack the tumour. However, as the tumour grows, it devises ways to suppress this activity of the T-cells.
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Themes Of Choice
As Savvy Investors Seek New Avenues, Thematic Mutual Funds Are Gaining Popularity
A golden girl
One of India's most formidable beauties passed away earlier this month. The odd thing is she would absolutely hate this obituary; she hated being written about and avoided publicity for all of her nine decades. Indira Aswani was 93 when she died. But anyone who encountered her, even briefly, was in such awe of her grace and poise, and one could not but remember her forever.
The interest in wine is growing delightfully in India
The renowned British wine writer and television presenter Jancis Robinson, 74, recently came to Delhi and Mumbai to reacquaint herself with India's wine industry. This was the Robinson's fourth visit to India; the last one was seven years ago. On this trip, Robinson and her husband, restaurateur Nicholas Lander, were hosted by the Taj Hotels and Sonal Holland, India's only Master of Wine.
United in the states
Indian-Americans coming together under the Democratic umbrella could get Harris over the line in key battlegrounds
COVER DRIVE
Usage-driven motor insurance policies offer several benefits
GDP as the only measure of progress is illogical
Dasho Karma Ura, one of the world's leading happiness experts, has guided Bhutan's unique gross national happiness (GNH) project. He uses empirical data to show that money cannot buy happiness in all circumstances, rather it is family and health that have the strongest positive effect on happiness. Excerpts from an interview:
India is not a controlling big brother
Prime Minister Tshering Tobgay considers India a benevolent elder sibling as the \"big brotherly attitude\" is happily missing from bilateral ties. He thinks the relationship shared by the two countries has become a model of friendship not just for the region, but for the entire world. \"India's attitude is definitely not of a big brother who is controlling and does not allow the little brother to blossom and grow,\" says Tobgay in an exclusive interview with THE WEEK.
Comrade with no foes
Lal Salaam, Comrade Yechury-you were quite a guy!
Pinning down saffron
In her first political bout, Vinesh Phogat rides on the anti-BJP sentiment across Haryana
MAKE IN MANIPUR
Home-made rockets and weapons from across the border are escalating the conflict