Celine Halioua Drops into a crouch and greets Bocce, a Chihuahua-dachshund mix with soulful brown eyes, like a long-lost friend. "Oh my god, you’re so beautiful!” she chirps. The two have just met in an upstairs room at Muttville Senior Dog Rescue in San Francisco, where light streams in through the open windows and urine occasionally streams onto the floor. About a dozen elder dogs, none taller than a kneecap, putter around on the gray linoleum or nap on blankets. When Halioua kneels, her dark hair tumbling over her shoulder, Bocce rests his head blissfully in her lap.
A tragedy of human-canine relations is that a 10-year-old dog such as Bocce is elderly, while a 28-year-old person such as Haliouais in the prime of life. Bocce is one of the lucky ones. Many dogs can only dream of living as long as he likely will, because dog lifespan is inversely correlated with body size. It’s the opposite of the wider pattern in the animal kingdom, where elephants easily outlast mice, which in turn outlive mosquitoes. A Chihuahua can expect roughly 15 years of life; an Irish wolfhound or Great Dane around seven or eight.
Halioua hopes that the startup whose name is emblazoned on her slim black T-shirt—Loyal—can start to fix this bug in humanity’s 14,000-year-plus wolf bioengineering project. The company, which she founded in 2019 and leads as CEO, is developing drugs to delay aging in dogs and extend their healthy lifespan. She has raised around 58 million and has two drugs in development. In a few years, she hopes to have the first commercial drug—for any species—to state on the label that it delays aging or extends lifespan. That alone would be a triumph, but Halioua sees it as a springboard to a still greater feat: creating similar drugs for humans.
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Spin Cycle - To study tornadoes, it helps to wear a skirt (and rocket launchers).
To study tornadoes, it helps to wear a skirt (and rocket launchers). When the Dominator is about to intercept a tornado, Timmer uses a two-prong system to anchor the vehicle. Air compressors lower the car so its thick rubber skirt nearly touches the ground, and spikes wedge 6 inches into the earth to firmly prevent the vehicle from liftoff. Timmer and ONeal have seen roughly 65 tornadoes in the past six months. It was a historic amount, ONeal says. A lot of meteorological setups are busts, but every day we drove out this year, we felt like we would see a tornado.
Fantastic Plastic - a plastic bag might be the most overengineered object in history.
Stretchy seaweed. Reverse vending machines. QR-coded take-out boxes. To cure our addiction to disposable crap, we'll all need to get a little loony.
Piece of Mind - This diagram maps 1 cubic millimeter of the brain-but its unprecedented clarity deepens the mysteries of cognition.
This diagram maps 1 cubic millimeter of the brain-but its unprecedented clarity deepens the mysteries of cognition. Although this image wouldn't look out of place on a gallery wall alongside other splashy works of abstract art, it represents something very real: a 1-cubic-millimeter chunk of a woman's brain, removed during a procedure to treat her for epilepsy. Researchers at Harvard University stained the sample with heavy metals, embedded it in resin, cut it into slices approximately 34 nanometers thick
I Am Laura Kipnis-Bot, and I Will Make Reading Sexy and Tragic Again
WHEN A FLATTERING EMAIL ARRIVED inviting me to participate in an AI venture called Rebind that I'd later come to think will radically transform the entire way booklovers read books, I felt pretty sure it was a scam.
DAMAGE CONTROL
According to Léna Lazare, the 26-year-old face of the radical climate movement, they're also acts of joy.
AN IMPERFECT STORM
CAN THE U.A.E. REALLY MAKE RAIN ON DEMAND OR IS IT SELLING VAPORWARE?
THE HOLE IN THE MAP OF THE WORLD
ON THE SURFACE, THERE'S NOTHING UNUSUAL ABOUT IT. JUST A SPOT OF OCEAN. BUT BENEATH THE WAVES LURKS SOMETHING INCREDIBLE: A MASSIVE WATERFALL. AND IN ITS MYSTERIOUS DEPTHS, THE FATE OF THE WORLD CHURNS.
COOLER HEADS
The deadliest environmental threat to city dwellers worldwide isn't earthquakes, tornadoes, flooding, or fire. It's heat.
TERMINAL VELOCITY
IT WAS 2 AM at Denver International Airport, and Jared Murphy was only a few hours into a planned 17-hour layover.
THE ETERNAL TRUTH OF MARKDOWN
If the robots take over, we should at least speak their language.