![CAR T-CELL THERAPY: A PROMISING CANCER TREATMENT ADVANCEMENT](https://cdn.magzter.com/1447759615/1717505077/articles/CRa0X0jrq1717531009744/CAR-TCELL-THERAPY-A-PROMISING-CANCER-TREATMENT-ADVANCEMENT.jpg)
For many decades, cancer treatment has relied on surgery, chemotherapy, and radiation therapy. Over the past decade, immunotherapy, therapies that stimulate and strengthen the power of a patient's immune system to attack tumors, has rapidly become an important cog in the wheel of cancer treatment. One form of immunotherapy, called CAR T-cell therapy, has generated tremendous excitement among researchers and oncologists alike.
Chimeric antigen receptor (CAR)-T ceolls are genetically modified T cells that are collected from a patient's blood and modified in the lab to express a tumor antigen-specific cell- which has the specificity of antigen-binding domain from a B cell receptor making it specific for a type of the target cell, and it is fused to the intracellular domain of a CD3 T cell giving it the cytotoxic power to kill the specific cancer cell, hence the name Chimeric antigen receptor (CAR)-T cell.
EXPANDING THE REACH
Efforts are underway to address challenges related to manufacturing and scalability. Streamlining the production process and increasing the accessibility of CAR T-cell therapy could make it more readily available to patients around the world. India has a handful of companies which have either already received DCGI approval, or are in the process of receiving the same.
The Food and Drug Administration (FDA) has approved six CAR-T cell therapies for hematological cancers (blood cancers) since 2017. Kymriah (tisagenlecleucel) and Yescarta (axicabtagene ciloleucel) were the first two CAR-T products to receive approval. They are used for treating patients up to 25 years old with refractory or relapsed B-cell precursor acute lymphoblastic leukemia (ALL), and adults with refractory or relapsed diffuse large B-cell lymphoma (DLBCL) after two or more lines of systemic therapies.
ãã®èšäºã¯ Healthcare Radius ã® June 2024 çã«æ²èŒãããŠããŸãã
7 æ¥éã® Magzter GOLD ç¡æãã©ã€ã¢ã«ãéå§ããŠãäœåãã®å³éžããããã¬ãã¢ã ã¹ããŒãªãŒã9,000 以äžã®éèªãæ°èã«ã¢ã¯ã»ã¹ããŠãã ããã
ãã§ã«è³Œèªè ã§ã ?  ãµã€ã³ã€ã³
ãã®èšäºã¯ Healthcare Radius ã® June 2024 çã«æ²èŒãããŠããŸãã
7 æ¥éã® Magzter GOLD ç¡æãã©ã€ã¢ã«ãéå§ããŠãäœåãã®å³éžããããã¬ãã¢ã ã¹ããŒãªãŒã9,000 以äžã®éèªãæ°èã«ã¢ã¯ã»ã¹ããŠãã ããã
ãã§ã«è³Œèªè ã§ã? ãµã€ã³ã€ã³
![ADDRESSING INDIA'S RURAL CARE GAP](https://reseuro.magzter.com/100x125/articles/11949/1721971/QpJDba1-v1717528537557/ADDRESSING-INDIAS-RURAL-CARE-GAP.jpg)
ADDRESSING INDIA'S RURAL CARE GAP
Lakhs of rural Indians lack access to healthcare services. Learn the ways India can improve healthcare accessibility in its rural areas.
![iMeUsWe unveils at-home DNA testing services](https://reseuro.magzter.com/100x125/articles/11949/1721971/K3Nxgy-pY1717531240311/IMEUSWE-UNVEILS-ATHOME-DNA-TESTING-SERVICES.jpg)
iMeUsWe unveils at-home DNA testing services
iMeUsWe and MapMyGenome's at-home DNA testing to offer health and ancestry insights.
![CAR T-CELL THERAPY: A PROMISING CANCER TREATMENT ADVANCEMENT](https://reseuro.magzter.com/100x125/articles/11949/1721971/CRa0X0jrq1717531009744/CAR-TCELL-THERAPY-A-PROMISING-CANCER-TREATMENT-ADVANCEMENT.jpg)
CAR T-CELL THERAPY: A PROMISING CANCER TREATMENT ADVANCEMENT
Employing genetically modified immune cells to attack tumors, CAR T-cell therapy offers new hope for cancer patients.
![LEADING WITH INNOVATION](https://reseuro.magzter.com/100x125/articles/11949/1721971/Eot0sz3dp1717530674027/LEADING-WITH-INNOVATION.jpg)
LEADING WITH INNOVATION
\"Every regional market presents a unique set of challenges and opportunities,\" said Ms Zahabiya Khorakiwala, Managing Director, Wockhardt Hospitals Group, during Healthcare Radius Leadership Vidcast.
![OVERCOMING INDIA'S AMR CHALLENGE](https://reseuro.magzter.com/100x125/articles/11949/1721971/Czk0Dfw861717529827618/OVERCOMING-INDIAS-AMR-CHALLENGE.jpg)
OVERCOMING INDIA'S AMR CHALLENGE
India faces a growing threat of antimicrobial resistance (AMR). Experts warn of superbugs and ineffective treatments. Is there hope? Read on to find out.
![SOCC launches online second opinion for pediatric care](https://reseuro.magzter.com/100x125/articles/11949/1721971/kJohnxHEg1717528431949/SOCC-LAUNCHES-ONLINE-SECOND-OPINION-FOR-PEDIATRIC-CARE.jpg)
SOCC launches online second opinion for pediatric care
SOCCâs online second opinion consultations for pediatric care aims to bridge the gap in pediatric healthcare services in India.
![Clove Dental opens 12 clinics in a single day](https://reseuro.magzter.com/100x125/articles/11949/1721971/TjdDlLAD_1717528387485/CLOVE-DENTAL-OPENS-12-CLINICS-IN-A-SINGLE-DAY.jpg)
Clove Dental opens 12 clinics in a single day
Clove Dental marks its 13th anniversary with nationwide expansion. Get full details.
![BM Birla Heart Hospital launches cardiac care program](https://reseuro.magzter.com/100x125/articles/11949/1721971/tOncTD6T11717528307325/BM-BIRLA-HEART-HOSPITAL-LAUNCHES-CARDIAC-CARE-PROGRAM.jpg)
BM Birla Heart Hospital launches cardiac care program
BM Birla Heart Hospital partners with Dozee for Al-powered cardiac care program.
![PD Hinduja Hospital goes digital for infection control](https://reseuro.magzter.com/100x125/articles/11949/1721971/QxzERzhxM1717528249727/PD-HINDUJA-HOSPITAL-GOES-DIGITAL-FOR-INFECTION-CONTROL.jpg)
PD Hinduja Hospital goes digital for infection control
Ropes in Ibhar Technologies for infection control, patient safety, and auditing automation.
![Maruti Suzuki marks one year of cardiac care in rural Gujarat](https://reseuro.magzter.com/100x125/articles/11949/1721971/-nO0Td2kp1717528186031/MARUTI-SUZUKI-MARKS-ONE-YEAR-OF-CARDIAC-CARE-IN-RURAL-GUJARAT.jpg)
Maruti Suzuki marks one year of cardiac care in rural Gujarat
Maruti Suzuki celebrates one year of providing advanced cardiac care in rural Gujarat.