Researchers are attempting to make egg cells without human ovaries.
In 2016, two Japanese reproductive biologists, Katsuhiko Hayashi and Mitinori Saitou, made an announcement in the journal Nature that read like a science-fiction novel. The researchers had taken skin cells from the tip of a mouse’s tail, reprogrammed them into stem cells, and then turned those stem cells into egg cells. The eggs, once fertilized, were transferred to the uteruses of female mice, who gave birth to ten pups; some of the pups went on to have babies of their own. Gametes are the cells, such as eggs and sperm, that are essential for sexual reproduction. With their experiment, Hayashi and Saitou provided the first proof that what’s known as in-vitro gametogenesis, or I.V.G.—the production of gametes outside the body, beginning with nonreproductive cells—was possible in mammals. The mice that had descended from the lab-made egg cells were described as “grossly normal.”
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TAKE TWO
\"The Hills of California\" and \"Yellow Face\" come to Broadway.
DOWNWARD SPIRALS
Missy Mazzoli's \"The Listeners\" and Jeanine Tesori's \"Grounded.\"
IT TAKES A VILLAGE
The exuberant, complicating drawings of the Shakers.
THE LONG CON
Rachel Kushner's anti-spy, anti-realism novel.
IF MEMORY SERVES
John Lewis knew how to put a legacy of heroism.
SILICON VALLEY'S INFLUENCE GAME
From crypto to A.I., tech titans are pouring money into super PACS to savage their political opponents.
WHEN THE ICE MELTS
What the fate of the Arctic means for the rest of the Earth.
SLEEP ESSENTIAL FOR HEALTH
To achieve good health, you must maintain a regular sleep schedule, and be able to get back to sleep once you are awake.
THE K-POP KING
Chairman Bang is bringing his formula for creating idols to the U.S.
THE SIGHTED WORLD
Growing up with the writer Ved Mehta.