Analysing the modifiable lifestyle risk factors for Gynaecological cancers there is growing evidence that supports obesity’s involvement in these cancers.
Obesity has tripled in women from 1975 to 2016 when WHO declared it as a non-communicable disease pandemic. Higher BMI values correlated with significant increase in death rates from Gynaecological cancers despite the availability of improved treatment modalities. It is seen that inflammatory mediators in fat tissue may predispose to altered cancer biology and disease promotion Obesity along with high blood pressure, high blood sugar levels, low levels of good cholesterol are components of Metabolic syndrome that has been associated with cancers…especially Uterine cancer.
Smoking is another risk factor which increase the risk of Gynaecological cancers. Smoking weakens the immune system and as a result of which and the by-product of tobacco which acts as a chemical carcinogen one becomes susceptible to HPV (human papilloma virus) infection in the cervix.
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