The Hornets had just three efforts on target from 20 attempts, with striker Vakoun Bayo especially profligate.
Bayo struck shots wide in both halves as Watford dominated a Plymouth side that were always dangerous on the counter-attack.
Ismael said: "I am really pleased with the performance. We said yesterday that it is important that we put these performances in with consistency and with the right mentality.
"But we were not ruthless enough. We put ourselves in great positions and we played some great football, but when you miss opportunities, you keep your opponent in the game and they think that they can maybe get more than one point.
"We are on the right path. As long as the players are brave, I will accept mistakes.
"I know Bayo is disappointed that he didn't get a goal, but it's important that you create chances. He worked hard and I'm sure he will get better when he gets his fitness."
There was little wrong with the attacking ambition of Ismael's side yet, for all their dominance, they were thwarted by both their own profligacy and defiant Plymouth defending.
With just over seven minutes gone, Matheus Martins clipped over a cross which fell invitingly for Bayo to strike on the swivel. His volley missed a post by inches.
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