While moisture in pharmaceutical packaging can have negative or even dangerous effects on its content, unpleasant odours are especially repellent to patients. Both can be systematically prevented using suitable adsorbents – provided the right aspects are taken into account.
Many pharmaceutical products such as tablets and capsules, but also test strips or inhalers are sensitive to moisture. The effects of moisture are manifold and often pose a high risk not only to the drug but also to patients. In the case of tablets, powders and effervescent tablets, the properties and texture may change, whereas gel capsules might dissolve due to moisture. Blood or urine test strips may produce false or misleading results if the test chemical is influenced by too much humidity.
In the worst case, the efficacy of drugs is reduced, or the analytical results are falsified, which can lead to an incorrect medication and impede successful therapy. In addition, many pharmaceuticals, especially analgesics such as acetylsalicylic acid, release specific molecules into the ambient air inside the packaging that can develop very unpleasant odours.
Only real data provides reliable results
The amount of humidity that penetrates into the packaging is decisive for the stability of a moisture-sensitive drug. Around 65% of humidity ingress can be attributed to the packaging. Weak spots can be the packaging wall, the sealing surfaces between containers and closures, as well as the sealing seams of blister packs. Hence the choice of the primary packaging depends mainly on maintaining the optimum climate inside the packaging in order to ensure the required shelf life.
Denne historien er fra July 2018-utgaven av Pharma Bio World.
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Denne historien er fra July 2018-utgaven av Pharma Bio World.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
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B&R Expands Gilgenberg Site
Automation specialist invests in production, office space and logisticsB&R is investing in its Gilgenberg site, located a few kilometers from the B&R headquarters in Eggelsberg. The expansion adds new offices, training rooms and production space. A new logistics hall has also been opened at the site.
Creating An Annual Event Of The Biopharma Industry By Focusing On Frontiers, & Promoting Leading Enterprises To Collaborate
The Union Budget 2018 was presented on February 1, 2018.
Pain Point To Gaining Brownie Points: Technology Is A Game Changer For Indian Pharma Sector
The Indian pharmaceutical industry has come a long way from traditional home-made herbal medicines to being the manufacturer of world class life-saving drugs. However, at the helm of game-changing innovations steering this industry to a whole new level is the implementation of technology.
Data Acquisition, Evaluation And Transmission To The Cloud
A single device to acquire data, evaluate it and send it to the cloud – that’s now possible with B&R’s Edge Controller. The powerful industrial PC can even be used for big data analysis and machine learning, while at the same time serving as a full-fledged industrial controller.
Just The Right Dose Of Intelligence
Nothing herein shall constitute an offer to sell, or a solicitation of an offer to buy. The ACOPO Strak product is not available for sale into the United States of America until September 2018.
Considerations For Extraction, Stabilization And Quantification By PCR For Sensitive Sample Such As RNA
This article talks about careful selection of an extraction system that helps stabilize and protect targets, especially RNA, or which allows for immediate analysis.
Novel Research In Pharmaceuticals And Bio-Pharmaceuticals
This article covers entire spectra of pharmaceutical research and as well as those related to synthesis and processing of pharmaceuticals.
Boost Productivity With Anti-sloshing
Transport liquids faster without spills With B&R’s industrial transport system, it is now possible to transport liquids quickly with no spills. SuperTrak is the only system on the market to offer anti-sloshing technology. This technology suppresses the format ion of oscillations on free surfaces to prevent liquids from spilling over container edges during transport .
Rational Use Of Drugs And Irrational Drug Combinations
Irrational use of medicines is a global phenomenon. Rational use of drugs may be defined as: Patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and the lowest cost to them and their community. Overuse, polypharmacy and incorrect use of drugs are the most common problems of drug use today. Irrational use of drugs may result due to various reasons at various levels including the prescribing errors and over the counter drugs. Irrational use of medicines may lead to serious negative health and economic consequences. Many irrational drug combinations are available in the Indian market. Proper implementation of rational use of drugs will improve the quality of life and result in better community healthcare.
Cold Chain Management For Sensitive Goods
Packaging, route planning and risk analysis ensure safe conditions during transportation of delicate drugs. Drugs are sensitive goods to transport, which can be subject to irreversible damage if they are stored or transported at temperatures outside the tolerated range. If the temperature falls below or rises above the specified range the quality of drugs requiring refrigeration can be seriously affected and they may cease to be effective. This article therefore describes how transport conditions during the transportation of drugs can be optimised through suitable packaging, individualised process design, the analysis and assessment of potential risks and close collaboration between the sender and the freight carrier.
