A brief history of tablet coating
The coating process was started first in the ninth century. A variety of materials was used to coat pills, such as talc, gelatin, and sugar. The first sugar-coated pill produced in the US came out of Philadelphia in 1856. Coating resistance to enteric or gastric fluid was developed in 1880. The film-coated tablet was marketed in the year 1954 for the first time.
There is a need for tablet coating in the pharma, Nutra, and food industries. Tablet coating is one of the oldest pharma processes still in existence. In recent years, pharma formulation in tablet coating made remarkable development; efforts were made to ensure durability as well as to improve the quality of the finished product.
Tablet coating is an essential technique of spraying a thin polymer-based film to the outer area of tablets or pellets, which consists of active ingredients. The primary aim of coating is to give protection from gastric fluid and physical stress. Different techniques of tablet coating such as sugar coating, film coating, and enteric coating are used commonly. There is a continuous effort to overcome the drawbacks of older coating techniques.
Coated tablets are defined as tablets covered with one or more layers of a mixture of various substances such as natural or synthetic resins, gums, inactive and insoluble filler, sugar, plasticizer, polyhydric alcohol, waxes, authorized coloring material, and sometimes flavoring material. The coating may also contain an active ingredient. Substances used for coating are usually applied as solution or suspension under conditions where the vehicle evaporates.
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Denne historien er fra April 2021-utgaven av Express Pharma.
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