The Shih Tzu siblings - thought to only be around 12 weeks old - were found in a black bin liner at the side of a bin in Atherton, the RSPCA said.
One of the puppies had already died.
The other was taken in for emergency veterinary care but died from parvovirus - a highly contagious disease in dogs.
The RSPCA has now launched an investigation to try and find the person who dumped the 'terrified' pups.
Animal welfare officer Steve Wickham said if they had not been found, the puppy that was still alive would have suffered a slow and lingering death.'
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Denne historien er fra February 27, 2022-utgaven av MEN on Sunday.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
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Sharks suffer trying times after slipping to heavy Bath defeat
SALE Sharks conceded six tries as Bath powered their way to 40-13 Gallagher Premiership win.
Red flags are flying over Josh signing
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Madrid stars are the ones that got away
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Historic pub's new look after refurbishment
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Bumpyroad ahead in electric car drive
TRAINS and buses may get more column inches, but the North of England is a region that remains dependent on cars to get around.
Ketamine explosion has echoes of heroin epidemic
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Influencer Kitty up for top award
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£18,000 raised in memory of paddleboarder
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Chopshop gang even posed as airport valets
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