![Researchers say they’ve finally sequenced the entire human genome. Yes, all of it](https://cdn.magzter.com/1439560219/1660829349/articles/pho-JiHUJ1661152498876/RESEARCHERS-SAY-THEYVE-FINALLY-SEQUENCED-THE-ENTIRE-HUMAN-GENOME-YES-ALL-OF-IT.jpg)
IN JUNE 2000, SCIENTISTS ANNOUNCED THE first draft of the human genome sequence had been completed. Generating the sequence was a technical feat – one that allowed scientists to begin reading humanity’s genetic blueprint – but it was still missing about eight per cent of the genome.
Now, an international consortium of about 100 scientists, dubbed the Telomere-to-Telomere (T2T) Consortium, say they’ve finally assembled the human genome in its entirety. If their work, which was published on 27 May 2021 to the preprint website bioRxiv, holds up to peer review, it could change the future of medicine. As researchers become more familiar with humanity’s genetic code, they can, for example, make more precise and effective medicines – including the kind of gene focused treatment that powered the first effective COVID-19 vaccines.
The first draft led to a boom in technology, like CRISPR, and therapeutics, but scientists didn’t realise how incomplete the draft was at the time, says Karen Miga, PhD, a genomics researcher at the University of California, Santa Cruz, and a member of the T2T Consortium.
Denne historien er fra September/October 2022-utgaven av Popular Mechanics South Africa.
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Denne historien er fra September/October 2022-utgaven av Popular Mechanics South Africa.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
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Can a retired rocket engine take us to Mars?
The space shuttle's main engine was mothballed with the programme in 2011. Now NASA believes it's the future of interplanetary travel.
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6 metre waves. All engines on fire. 1 500 Km from land.
How Flying Tiger 923 and its 'miracle pilot' made an impossible ocean landing.
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Land Rover Discovery D300
A FEW MONTHS ago a $2 billion lottery jackpot was won in the United States. It’s fun to sometimes ponder outrageous winnings like that, and how I’d spend it, even if it’s completely detached from reality.
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Volkswagen Taigo R-Line 1.0 TSI
The compact proportions make this a delightful daily commuter.
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Mazda CX-5 2.2 L De Akera AWD
Floor the pedal and overtaking is achieved easily and safely.
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Making the most out of your grinder
THE HUMBLE BENCH GRINDER IS A STAPLE of the handyworker's home shop, largely due to its versatility. But, while you can employ one to remove metal from just about anything, the traditional kind may not provide the precision you need for every grinding operation. Here, we shed light on the best ways to use the different types of grinders, gleaned from our testing.
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Unlock your devices' full potential with a USB-C hub
AS NEW TECH SHRINKS EACH YEAR, essential ports such as USB-A, HDMI, and ethernet are being replaced by the slimmer USB-C.
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WE BUILT THE WORLD'S FIRST V-8 TESLA
THE RICH REBUILDS TEAM HAD A DEAD MODEL S. THEY FIXED IT WITH A CAMARO ENGINE.
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I bought a GHOST TOWN
This abandoned California mining village once had 400 buildings. Now I'm restoring the 20 that remain.
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F1 taught me that speed starts with comfort
AS A FAN OF MOTORSPORT, I'M ALWAYS fascinated with the finer details that go into Formula One racing. Piloting the fastest racing cars on the planet subjects drivers to savage forces - up to 6 G's under braking which has led to an almost endless pursuit of comfort.