Singapore is a leading startup hub in Asia having the expertise and network to be the launch pad to the region and beyond. Singapore’s A*STAR spin-offImmunoScape, a pre-clinical biotechnology company focused on the discovery and development of next-generation T-cell receptor (TCR) cell therapies in the field of oncology has been thriving in the regional and global space. In an interaction with BioSpectrum Asia, Ng Choon Peng, Founder & CEO at Immunoscape discussed the opportunities and challenges in commercialising technology spin-outs from biomedical research amidst Singapore’s fast-growing ecosystem for bioscience ventures. Edited excerpts;
How crucial is the adaptation of next-generation TCR cell therapies for diagnostic and prophylactic purposes?
TCR cell therapies have evolved from their initial ventures around the isolation, expansion and re-infusion of T-cells to the patient, to newer and exciting ways of devising novel TCR cell therapies. As cell therapies are designed to be highly specific to a patient’s tumour these are built using cutting-edge, in-silico Machine Learning approaches that can improve efficacy and patient safety.
While current TCR technologies primarily address unmet treatment options, next-generation TCR cell technologies could potentially include the following:
● Diagnostic use cases such as the development of patient stratification tools, i.e., by identifying variations in antigen-specific T-cells within patient groups for a deeper understanding of the pathology. This ensures that the right drugs reach the right patients at specified times
Denne historien er fra BioSpectrum Asia Feb 2023-utgaven av BioSpectrum Asia.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
Allerede abonnent ? Logg på
Denne historien er fra BioSpectrum Asia Feb 2023-utgaven av BioSpectrum Asia.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
Allerede abonnent? Logg på
Promega unveils GloMax Galaxy Bioluminescence Imager for illuminating protein dynamics in real time
US-based Promega Corporation, a life-sciences research partner dedicated to providing intuitive tools that empower scientists to innovate, has unveiled the new GloMax Galaxy Bioluminescence Imager.
Singleron and Bioscreen to enhance access to single cell multi-omics solutions for Indian researchers
Singleron Biotechnologies, a leading innovator in single cell multi-omics solutions, has announced a strategic partnership with Bioscreen, a renowned distributor of advanced life science products in India.
Eppendorf brings CO2 incubator shaker with integrated 180 °C sterilisation routine
Eppendorf has announced the launch of a CO2 incubator shaker with integrated 180 °C sterilisation routine.
Waters introduces new bioseparations tools to improve development of RNA-based vaccines using LC-MS analysis
US-based Waters Corporation has introduced a comprehensive set of sample preparation enzymes, reagents, and waters_connect software that simplify sequence and modification confirmation of large molecule RNA therapeutics using liquid chromatography-mass spectrometry (LCMS) analysis.
Singapore designs novel gene therapy offering hope for epilepsy patients
Researchers from the Yong Loo Lin School of Medicine, National University of Singapore are working on a therapy that holds potential in treating patients with epilepsy, a neurological disorder defined by recurring seizures due to abnormal brain activity.
Spider venom heart drug moves to clinical trials in Australia
A University of Queensland (UQ)-led project in Australia to develop the first-ever drug to treat heart attack and protect donor hearts will move to human clinical trials, after receiving $17.8 million in funding from the Medical Research Future Fund (MRFF).
India develops portable ultrasound scanner for sports injury diagnosis
A team of researchers at the Indian Institute of Technology Madras (IIT-M) has developed an indigenous portable Point-of-CareUltrasound (POCUS) Scanner for sports injury diagnosis and management.
Integris appoints medtech veteran Probir Das as new CEO
Integris Healthcare, a global diversified medical technology company, has announced the appointment of Probir Das as Chief Executive Officer (CEO). He will join effective November 2024 and will be based in New Delhi.
Clarity Pharma promotes Michelle Parker to CEO
Australia-based Clarity Pharmaceuticals has announced the appointment of Michelle Parker as Chief Executive Officer (CEO), effective from October 11, 2024.
Dr Makoto Sugita steps in as President of Nxera Pharma Japan
Nxera Pharma Co., formerly known as Sosei Group or Sosei Heptares, has announced the appointment of Dr Makoto Sugita, as President of Nxera Pharma Japan, and Executive Officer, Executive Vice President and Chief Medical Officer (CMO) of Nxera Pharma.