When You Know You Might Forget Everything
New York magazine|July 15-28, 2024
LIVING WITH THE ALZHEIMER'S GENE.
AMELIA SCHONBEK
When You Know You Might Forget Everything

IN 2017, 23andMe began offering tests for the genetic risk of developing certain health conditions like celiac disease, Parkinson's, and late-onset Alzheimer's. The Alzheimer's test will tell you if you have the gene variant APOE4, which means you have an increased likelihood of developing the disease. One in four people carry a single copy of the gene, but 2 to 3 percent of the population have two copies-one from each parent-and have a much higher probability. As with all of 23andMe's upcharged "Health Predisposition Reports," the sell on it was self-empowerment: Once you know, you can plan, allowing you to take charge of your well-being.

Except most experts don't recommend that you test for APOE4 status. There's no cure for Alzheimer's disease and no surefire way to prevent it. Many people who find out they have two copies of APOE4 from 23andMe are left only with profound anxiety.

Not taking the test in a clinical setting means that when the results come in, there is no doctor or counselor present to help process them or explain what can even be done with the information. Instead, there's the internet: In Facebook groups and Reddit forums, APOE4/4's, as they call themselves, try to help one another through their doom spirals. They parse scientific studies on the links between exercise and cognition and theorize about the protective benefits of fish-oil supplements and cooking with saffron.

"I AM OPTIMISTIC, BUT I HEAR THIS CLOCK TICKING IN THE BACK OF MY HEAD."

Denne historien er fra July 15-28, 2024-utgaven av New York magazine.

Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.

Denne historien er fra July 15-28, 2024-utgaven av New York magazine.

Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.

FLERE HISTORIER FRA NEW YORK MAGAZINESe alt
Trapped in Time
New York magazine

Trapped in Time

A woman relives the same day in a stunning Danish novel.

time-read
6 mins  |
Nov 18-Dec 1, 2024
Polyphonic City
New York magazine

Polyphonic City

A SOFT, SHIMMERING beauty permeates the images of Mumbai that open Payal Kapadia's All We Imagine As Light. For all the nighttime bustle on display-the heave of people, the constant activity and chaos-Kapadia shoots with a flair for the illusory.

time-read
3 mins  |
Nov 18-Dec 1, 2024
Lear at the Fountain of Youth
New York magazine

Lear at the Fountain of Youth

Kenneth Branagh's production is nipped, tucked, and facile.

time-read
5 mins  |
Nov 18-Dec 1, 2024
A Belfast Lad Goes Home
New York magazine

A Belfast Lad Goes Home

After playing some iconic Americans, Anthony Boyle is a beloved IRA commander in a riveting new series about the Troubles.

time-read
5 mins  |
Nov 18-Dec 1, 2024
The Pluck of the Irish
New York magazine

The Pluck of the Irish

Artists from the Indiana-size island continue to dominate popular culture. Online, they've gained a rep as the \"good Europeans.\"

time-read
8 mins  |
Nov 18-Dec 1, 2024
Houston's on Houston
New York magazine

Houston's on Houston

The Corner Store is like an upscale chain for downtown scene-chasers.

time-read
3 mins  |
Nov 18-Dec 1, 2024
A Brownstone That's Pink Inside
New York magazine

A Brownstone That's Pink Inside

Artist Vivian Reiss's Murray Hill house of whimsy.

time-read
3 mins  |
Nov 18-Dec 1, 2024
These Jeans Made Me Gay
New York magazine

These Jeans Made Me Gay

The Citizens of Humanity Horseshoe pants complete my queer style.

time-read
2 mins  |
Nov 18-Dec 1, 2024
Manic, STONED, Throttle, No Brakes
New York magazine

Manic, STONED, Throttle, No Brakes

Less than six months after her Gagosian sölu show, the artist JAMIAN JULIANO-VILLAND lost her gallery and all her money and was preparing for an exhibition with two the biggest living American artists.

time-read
10+ mins  |
Nov 18-Dec 1, 2024
WHO EVER THOUGHT THAT BRIGHT PINK MEAT THAT LASTS FOR WEEKS WAS A GOOD IDEA?
New York magazine

WHO EVER THOUGHT THAT BRIGHT PINK MEAT THAT LASTS FOR WEEKS WAS A GOOD IDEA?

Deli Meat Is Rotten

time-read
10+ mins  |
Nov 18-Dec 1, 2024