Hemopoietic stem cell transplantation (HSCT) was developed in the early 1970s and was recognised as a potential treatment for a number of benign and malignant haematological diseases. Since then, the field has grown into a full specialty. Keeping pace with technological advances, this area has also seen evolution as regards to indications, availability of donor in family (an HLA identical sibling) or outside HLA matched unrelated donor (with the help of bone marrow donor registries) or haploidentical donor from parent or sibling.
In India, this treatment was started in 1983. The progress was slow initially, but has picked up in the last two decades. Currently, more than 110 centres are doing transplant. As per the Indian Society of Blood and Marrow Transplantation Registry, 23,843 patients underwent HSCT till 2021. Of these, 13,962 underwent allogenic HSCT (using stem cells from a donor), and 9,881 autologous HSCT (using patient's own stem cells). Multiple myeloma and lymphomas (Hodgkin's and Non Hodgkin's) are major indications for autologous HSCT, while acute myeloblastic leukemia (AML),ẞ-Thalassemia, severe aplastic anaemia and acute lymphoblastic leukemia are major indications for allogeneic HSCT.
Denne historien er fra December 01, 2024-utgaven av THE WEEK India.
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Denne historien er fra December 01, 2024-utgaven av THE WEEK India.
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Efficiency and innovation
As health care evolves, professionals must employ innovative methods to refine their skills
Level up
Only 30 per cent of needy patients are able to undergo transplant in India; we need more dedicated transplant centres
HOPE STEMS FROM A CELL
While stem cell therapies have shown success in treating blood disorders, orthopaedic ailments, autoimmune diseases and eye issues, there is hope that they can one day treat patients with heart disease, blindness, Parkinson's, HIV, diabetes and spinal cord injuries
Mind matters
Your mindset can limit or expand your physical ability
Cutting edge
Would you go under the knife if a robot was the one holding it? Or would you say, \"No way, I need a human touch\"? You might have to decide soon because a robot that can imitate skilled human surgeons is already here.
The smallest cut
Minimally invasive surgeries have a bright future, with virtual reality and 3D procedures offering greater precision and AI on the horizon
Signalling a revolution
Canadian scientist and entrepreneur Sachdev Sidhu is focused on bringing cutting-edge antibody engineering to his country of origin
Wellness on demand
Starting as a doctor-patient chat platform, Medibuddy has evolved to be India's largest on-demand, full-stack digital health care platform
HEARING AND VISION LOSS LINKED TO HEART DISEASE AND STROKE
A CHINESE STUDY PUBLISHED IN THE JOURNAL of the American Heart Association suggests that middle aged and older adults with sensory impairments, specifically hearing and vision loss, have an elevated risk of cardiovascular diseases, including stroke and heart attacks.
PETTICOAT CANCER AND THE SARI LINK
TYING YOUR UNDERSKIRT (petticoat) tightly around the waist when wearing a sari, can lead to \"petticoat cancer\" or \"sari cancer,\" as it was previously called. Tying the underskirt too tightly can cause constant cord friction that can lead to chronic inflammation, skin ulceration and, in rare cases, skin cancer.
