Rohit Kumar had lost all hope. All anti-tuberculosis drugs had stopped giving results for the 23-year-old from Delhi. As a last resort, his doctor asked him to undergo genome testing. Kumar (name changed) was found to be multidrug resistant (MDR). Fortunately, he had not reached the extensive drug-resistant stage. He was immediately put on a new drug regime and is now on the road to recovery. Like Kumar, there are several TB patients who are benefiting from genome sequencing, which helps to make the right diagnosis at the right time.
“Genomics is the future of effective tuberculosis diagnosis,” says Gunisha Pasricha, principal scientist, infectious disease expert, MedGenome, a genomics research and drug development organisation. “With advanced techniques like culturefree, whole genome sequencing (WGS), we are gradually progressing towards overcoming the challenges around accurate and timely diagnosis of tuberculosis.” As per a paper titled, ‘WGS of Mycobacterium TB Isolates from India’, published in Frontiers in Microbiology, “WGS of mycobacterium tuberculosis (MtB) has been constructive in understanding its evolution, genetic diversity and the mechanisms involved in drug resistance.” The study highlighted the immense significance of employing WGS in diagnosis as well as treatment.
Denne historien er fra April 07, 2024-utgaven av THE WEEK India.
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Denne historien er fra April 07, 2024-utgaven av THE WEEK India.
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Doctor's doctors
Internists deal with prevention, diagnosis and treatment of all kinds of diseases, while also coordinating with doctors across specialties
WORK THIS OUT!
What is the true cost of a 90-hour workweek? Reduced productivity, mental health issues and severe health risks, say doctors
The experience of oppression
The British enacted several laws that might appear liberal, only to then veto the invocation of progressive measures. Nevertheless, these milestones guided the founding fathers in conceiving and creating the Constitution of India
One, two, buckle my shoe!
“Darling,” I said to my life companion of more years than I care to remember, “Do you think there is any correlation between pain in the feet and attending prayer meetings?”“You really are a stupid old man!” said the light of my life. “Can’t you think of anything more bizarre so late at night?”
A helping hand
Over the past year, Imaginarium has placed 3D-printed parts in space, in human bodies, in oil fields in the Middle East, and as drones on the Indian border
Fading federalism
One of the most visible indicators of the erosion of state autonomy is the diminishing financial independence of states
FOUNDING MOTHERS OF THE CONSTITUTION
THEIR CONTRIBUTION IN THE MAKING OF THE REPUBLIC REMAINS EXEMPLARY AND INSPIRING
Value every breath
VO2 max is the best way to measure fitness and predict life expectancy
Statutes of unity
The Constitution reminds us that national oneness comes through addressing inequalities, not enforcing uniformity
Incomplete equality
Equal marriage rights is one of the last bastions of patriarchy and to dismantle it, the recognition of marital rape as an offence is non-negotiable
