Interim head coach Van Nistelrooy will hand over the reins to Ruben Amorim this week and wait to find out if he still has a job.
He will leave behind a team unbeaten in his four games, and with some momentum and goals behind them at last.
Bruno Fernandes opened the scoring inside 20 minutes with a delightful finish, to celebrate his 250th United appearance in style.
An own-goal from Victor Kristiansen doubled their advantage, before substitute Alejandro Garnacho sealed Leicester's fifth league defeat of the season with a stunning strike.
Van Nistelrooy had dropped Garnacho in favour of Amad Diallo, who scored twice in the win against PAOK in the Europa League last Thursday.
Centre-back pair Lisandro Martinez and Matthijs de Ligt were also recalled.
Denne historien er fra November 11, 2024-utgaven av Daily Express.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
Allerede abonnent ? Logg på
Denne historien er fra November 11, 2024-utgaven av Daily Express.
Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.
Allerede abonnent? Logg på
We won't call it quits on blitz
HENRY STILL CONVINCED SYSTEM WILL TAME BOKS
JACOB BATS AWAY THE SUDDEN HYPE
Bethell keeps a level head after rapid England impact
Open wound still stings for Rory
'IT'S ONE THAT GOT AWAY'
First test looming for Lewis
NEW YEAR REVOLUTION
STRAIGHT AS A DY
O'Brien star will not lack for fitness
Pie heir 'killed his friend in planned Christmas attack'
THE heir to a £230million pie empire murdered his housemate by stabbing him in a planned Christmas Eve attack, a jury was told.
Shoplift gang's £200k haul of luxury goods
THREE shoplifters who plundered supermarkets and walked away with luxury goods, including champagne worth £4,500, have been jailed.
Church requires 'a hurricane of change' to clean up its act
DAME Vera Baird wants more senior clerics to quit or be fired over Church of England abuse revelations.
£1.4m payout for mum flung from fairground ride
A MOTHER who suffered serious injuries when she was hurled from a fairground ride has agreed a £1.43million settlement.
Give Beeb's overpaid nonentities red card
IN AN increasingly bleak world, a piece of unmitigated good news is exceedingly welcome and here it is: Gary Lineker is stepping down from Match Of The Day.
