Sam, 29 and Joe, 22, played 20 minutes together last September in the Premiership Cup when Joe came off the bench vs Leicester, but the two will feature in the centres from the start as the Sharks continue their strong family tradition.
Another Sharks family name features in the backline in Luke James, whose brother, Sharks legend Sam, is currently scoring tries for Racing 92.
Alongside the returning Gus Warr and cup captain Tom Curtis, he's a more experienced head in an overall youthful side, exciting youngsters Alex Wills and Obi Ene retaining their spots on the wings.
In the pack, there's only one change as Rouban Birch comes in at number eight as one of six starters facing a former dual registration club in Caldy.
The squad was named by senior academy coach Gareth Harris, who is taking lead on Sale's Premiership Cup block and he's joined in the dugout by senior squad defence coach, Byron McGuigan.
Denne historien er fra November 08, 2024-utgaven av Manchester Evening News.
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Denne historien er fra November 08, 2024-utgaven av Manchester Evening News.
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Amad and, right, Harry Maguire AMORIM'S 'FINGERPRINTS' ALREADY ON UNITED
ARSENAL manager Mikel Arteta has said signs of Ruben Amorim's impact on United is 'very clear' ahead of tonight's Premier League meeting between the two clubs.
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United are leaving it late to trigger new deals for duo
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Pep convinced injury nightmare has robbed City of seat at table top
PEP Guardiola said that this City team would be top of the league without their injury crisis.
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