A DEVELOPING CRISIS
Down To Earth|July 16, 2023
Most big pharmaceutical companies have all but quit research and development of new antibiotics since it is a low-return venture. Rapid rise of antimicrobial resistance means the old ammunition is misfiring. Without effective antibiotics, global healthcare will lose the treatment framework it stands on. A report by AMIT KHURANA, RAJESHWARI SINHA and GAURI ARORA on the precipitating global health crisis
AMIT KHURANA, RAJESHWARI SINHA and GAURI ARORA
A DEVELOPING CRISIS

I WOULD PRAY very hard," says V Ramasubramanian, when asked what if antibiotics failed to work one day. For the Chennai-based doctor who specialises in infectious diseases and tropical medicines, it is just impossible to contemplate a world without these wonder drugs that have revolutionised modern medicine since Alexander Fleming discovered the first of the kind, penicillin, in 1928. Today, antibiotics underpin much of the treatment we receive-be it for a small scrape or an organ transplant. Scientists estimate that by preventing people from dying of bacterial infections, antibiotics have helped increase life expectancy by 23 years. But the progress made over the last century is getting eroded.

Repeated exposure to antibiotics, due to unnecessary use, has prompted these single-cell pathogens to mutate and evolve their defence mechanisms to inactivate or evade the drugs. A May 2023 study by UK researchers has found that some bacteria adapt special pumps to flush antibiotics out of their cells. Then there are those resistant to multiple drugs. Last year, a report by medical journal The Lancet found that antibiotic resistance is now a leading cause of death worldwide. In 2019, antibiotic resistance was linked to 5 million deaths, with 1.3 million deaths directly attributed to it.

Denne historien er fra July 16, 2023-utgaven av Down To Earth.

Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.

Denne historien er fra July 16, 2023-utgaven av Down To Earth.

Start din 7-dagers gratis prøveperiode på Magzter GOLD for å få tilgang til tusenvis av utvalgte premiumhistorier og 9000+ magasiner og aviser.

FLERE HISTORIER FRA DOWN TO EARTHSe alt
In leading role again
Down To Earth

In leading role again

MOVIES AND WEB SERIES ARE ONCE AGAIN BEING SET IN RUSTIC BACKGROUNDS, INDICATING A RECONNECT BETWEEN CINEMA AND THE COUNTRYSIDE

time-read
5 mins  |
December 16, 2024
One Nation One Subscription comes at a huge cost
Down To Earth

One Nation One Subscription comes at a huge cost

As top US universities scrap big deals with top scientific publishers, India’s ONOS scheme seems flawed and outdated

time-read
4 mins  |
December 16, 2024
Return of Rambhog
Down To Earth

Return of Rambhog

Bid to revive and sell the aromatic indigenous paddy variety has led to substantial profits for farmers in Uttar Pradesh's Terai region

time-read
4 mins  |
December 16, 2024
Scarred by mining
Down To Earth

Scarred by mining

Natural springs of Kashmir drying up due to illegal riverbed mining

time-read
5 mins  |
December 16, 2024
Human-to-human spread a mutation away
Down To Earth

Human-to-human spread a mutation away

CANADA IN mid-November confirmed its first human case of avian influenza, with a teenager in the British Columbia being hospitalised after contracting the H5N1 virus that causes the disease. The patient developed a severe form of the disease, also called bird flu, and had respiratory issues. There was no known cause of transmission.

time-read
1 min  |
December 16, 2024
True rehabilitation
Down To Earth

True rehabilitation

Residents of Madhya Pradesh's Kakdi village take relocation as an opportunity to undertake afforestation, develop sustainable practices

time-read
2 mins  |
December 16, 2024
INESCAPABLE THREAT
Down To Earth

INESCAPABLE THREAT

Chemical pollution is the most underrated and underreported risk of the 21st century that threatens all species and regions

time-read
10+ mins  |
December 16, 2024
THAT NIGHT, 40 YEARS AGO
Down To Earth

THAT NIGHT, 40 YEARS AGO

Bhopal gas disaster is a tragedy that people continue to face

time-read
8 mins  |
December 16, 2024
A JOKE, INDEED
Down To Earth

A JOKE, INDEED

A CONFERENCE OF IRRESPONSIBLE PARTIES THAT CREATED AN OPTICAL ILLUSION TO THE REALITY OF A NEW CLIMATE

time-read
10+ mins  |
December 01, 2024
THINGS FALL APART
Down To Earth

THINGS FALL APART

THE WORLD HAS MADE PROGRESS IN MITIGATING EMISSIONS AND ADAPTING TO CLIMATE IMPACTS. BUT THE PROGRESS REMAINS GROSSLY INADEQUATE

time-read
4 mins  |
December 01, 2024