Editing the heart
THE WEEK India|February 05, 2023
Is it possible to fully recover from a severe heart attack? A recent study by scientists at UT Southwestern Medical Center in Texas, published. in Science, suggests that with the help of gene editing, this may soon become reality.
Editing the heart

A heart attack happens when blood vessels are blocked and the heart is deprived of oxygen. An estimated 1.9 crore people die because of cardiovascular problems every year.

Recently, the scientific world discovered that much of the damage caused by a heart attack is triggered by the over-activation of a gene named CaMKII8 (calcium protein calmodulin-dependent kinase II8). This gene is a central mediator of several physiological processes in the heart; it has a crucial role in heart cell signalling and function. A part of CaMKIIS protein is made up of two methionine amino acids. When these two are oxidised-because the heart is stressed CaMKIIS gets overactivated.

This story is from the February 05, 2023 edition of THE WEEK India.

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This story is from the February 05, 2023 edition of THE WEEK India.

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