The study discovered hundreds of genetic variants involved in brain volume, also found in people with neurological disorders such as Parkinson's and Attention Deficit Hyperactivity Disorder (ADHD). Miguel Renteria, leader of the research project from QIMR, said that the discovery shows that some genetic variants influence brain structure and also influence risk of developing brain-related conditions, reported Xinhua news agency.Led by Renteria and colleague Luis Garcia-Marin, an international team of 189 scientists analysed DNA data and brain scans from 76,000 participants across 19 countries. They observed 254 genetic variants influencing the size of a person's brain structure and then studied if those variants were also implicated in the risk of developmental, psychiatric and neurological disorders."Genetic variants associated with larger brain volumes in key brain regions also increase risk of Parkinson's disease, while variants linked to smaller brain volumes in key regions are associated with an increased risk of ADHD," Renteria said."These findings suggest genetic influences that underpin individual differences in brain structure may be fundamental to understanding the underlying causes of brain-related disorders," he said.

Link between brain volume & disorders found

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